Shared patterns of protein sequence evolution are predictive of functional interactions in the network of proteins that control fertility and femalepost-mating behavior in the fruit fly, Drosophila melanogaster. Furthermore, steps in the network at which several newly identified proteins in the network act are consistent with their strongest evolutionary correlations.

http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1004108

Geoffrey D. Findlay, Jessica L. Sitnik, Wenke Wang, Charles F. Aquadro, Nathan L. Clark, Mariana F. Wolfner; PLoS Genetics, 2014;10: e1004108. [doi:10.1371/journal.pgen.1004108]

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